simple and efficient method for the preparation of 5-bromoisatins

نویسندگان

rahman hosseinzadeh

yaghoub sarrafi

hamid khaledi

چکیده

isatin, n-methyl isatin and n-benzylisatin were smoothly monobrominated in the 5-position by treatment with pyridinium bromochromate (pbc) in acetic acid medium. in the similar conditions indigo underwent bromination and oxidation to give 5-bromoisatin in high yield.

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Simple and Efficient Method for the Preparation of 5-Bromoisatins

Isatin, N-methyl isatin and N-benzylisatin were smoothly monobrominated in the 5-position by treatment with pyridinium bromochromate (PBC) in acetic acid medium. In the similar conditions indigo underwent bromination and oxidation to give 5-bromoisatin in high yield.

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عنوان ژورنال:
caspian journal of chemistry

ناشر: university of mazandaran

ISSN 1735-0611

دوره 1

شماره 1 2012

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